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8. Certainly most people would feel uncomfortable with a 17 year old with cancer being taken from her home and family by child services, forcibly treated with chemotherapy, and not be allowed to have contact with her family during that period. Ultimately, the question is do the ends justify the means?, and in this case I would have to say that they did not. In cases where the child is younger, I would say yes, but with a 17 year old, I just cant say that they do. @Lawrence Yes, they probably will blame the chemo, even though she initially went into remission. Many quacks especially homeopaths claim that conventional treatments somehow interfere with the nonexistent ability of their so called treatments to work. @Orac The GoFundMe page you quoted says in January of 2017 cassandra discovered that now both of her lungs are full of masses along with her surrounding lungs , chest , surrounding heart and neck . Cassandra now has to go through a very intensive 6 9 months of chemotherapy, again in hopes that things clear up. But at the bottom of your post, you write every week without effective treatment further diminishes the chances that Callender can be saved. I just hope she takes that chance and seeks real medical treatment instead of quackery as soon as possible. Doesnt the GoFundMe page state that she finally has sought real medical treatment, and is now undergoing chemotherapy?Yeah.
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6. Instead, they are operated under a high degree of microbial control, as can be provided by gamma irradiation without sterilization validation. Consideration of whether a process step must be validated as sterile, in contrast with maintaining a microbially controlled zero or low bioburden state, is critical to optimizing the time and cost requirements for process development. Similarly, when validated sterility is required, consideration whether an entire single use system or only the fluid path needs to be validated as sterile also can affect time and cost requirements. As mentioned previously, establishing and maintaining a validated claim of sterility for single use bioprocess systems or components can require significant cost that will be ultimately borne by their users. Particularly during process development and often during subsequent production, a claim of microbially control based on irradiation may be sufficient to prevent significant microbial contamination while also saving the time and cost of establishing and maintaining a validated sterile claim. This balance between added assurance of sterility afforded by a validated sterile claim and the substantial added cost to attain that added assurance is one that must be made by biopharmaceutical manufacturers. The choice must be made case by case and is most likely to be driven by a risk assessment of each unit operation as well as by the manufacturing process as a whole. In upstream processing, bacterial e. g. , Escherichia coli cell cultures tend to be operated in short time frames and are fairly resistant to overgrowth by low levels of contaminant bacteria.
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Those first watches were usually either carried in a pants or vest pocket attached to the end of a chain, or they were worn as a pendant attached to the end of a chain or a cord suspended around the neck. Watches worn on the wrist made sporadic appearance as early as the late 1500s. Queen Elizabeth I is said to have worn a watch encased in a bracelet. One of the first people known to have worn a wristwatch is the French mathematician and philosopher, Blaise Pascal 1623 1662. He attached his pocket watch to his wrist with a cord. The first wristwatch was actually invented in 1868 by Swiss watchmaker, Patek Phillipe. As interesting as it may seem, the wristwatch was not fully accepted by society at first. Wristlets, as they were called, were worn only by women as a fashion accessory. Delicate, hand made, gem encrusted wristwatches were worn by women of royalty as an expensive jewelry piece. At that time, it was considered more of a "passing fancy" rather than a serious timepiece, since few believed wristlets could be made to achie ve any level of accuracy, nor could they endure the rigors of daily human activities. In 1904, French jeweler, Louis Cartier, created the first man's wristwatch.